Institut Necker Enfants Malades (INEM) is a biomedical research center located on the Necker campus. It benefits from numerous state-of-the-art core facilities. The Campus has a long-standing reputation for scientific excellence and key pioneering medical contributions (transplantation, biotherapy, gene therapy). It provides a vibrant environment for basic research and translational innovation.

The host laboratory and project

The team is interested in the intestinal stem cell niche regulation in development, regeneration and pediatric pathologies. We use multi-disciplinary approaches such as organoids, microfabrication, genetically modified mice, and single cell multi-omics to study how stem cells interact with their microenvironment.

Your profile

We are looking for a Postdoctoral Researcher with cell culture and mouse handling background.

• On-the-job training will be provided for additional technics and according to the candidate’s interests.
• Experience in transcriptomics and/or image analysis is a plus!
• Highly motivated candidate with a strong sense of teamwork.
• English-speaking and the ability to work in a multicultural environment are essential

This is a full-time, 2 years fixed-term contract starting from March 2025 (renewal possible) + benefits.

How to apply

Please send a cover letter (max. 1 page) + CV including 2 contact details for reference in one PDF to @email 

Additional information

• Baghdadi MB et al. PIEZO-dependent mechano-sensing is essential for intestinal stem cell fate decision and maintenance. Science, 2024 o Baghdadi MB et al. Enteric glial cell heterogeneity regulates intestinal stem cell niches. Cell Stem Cell, 2021
• Baghdadi MB et al. Notch-induced Collagen V maintains muscle stem cells by reciprocal activation of the Calcitonin receptor. Nature, 2018
• Baghdadi MB et al. Notch induced mir-708 antagonizes satellite cell migration and maintains quiescence. Cell Stem Cell, 2018