Just published in JCI Insight: the team of Marco Pontoglio and the team of Fabiola Terzi, in collaboration with the pathology department of Necker hospital, have elucidated two key events in the pathophysiology of kidney damage in patients with COVID-19: (1) they demonstrated that SARS-CoV-2 infects living renal cells and that the infection is associated with increased death; (2) they showed that SARS-CoV-2 activates specific genetic networks and identified X-linked inhibitor of apoptosis-associated factor 1 as a critical target of SARS-CoV-2 infection. See more in: https://insight.jci.org/articles/view/165192