Welcome on the Necker-Enfants Malades Institute website
The Necker-Enfants Malades Institute is administered by one Director assisted by the two department Heads and one General secretary in charge the administration. Each PI or CoPI is responsible for his (her) scientific project and for the use of his (her) allocated space
Fabiola Terzi
INEM Director
Mario Pende
Marco Pontoglio
Director of "Growth and Signalling" Dept
Peter Van Endert
Simon Fillatreau
Director of "Immunology, Infectiology and Haematology" (I2H) Dept
Sabine Barbut
General Secretary
Research Teams
Twenty one research teams are founding members of the Necker-Enfants Malades Institute. The teams are grouped in two departments: a department of Cell biology (Growth and Signalling) and a department of, Immunology, Infectiology and Haematology (I2H). The Necker-Enfants Malades Institute currently comprises 103 senior scientists, one third of whom are medical doctors, 60 technicians and engineers, 35 postdoctoral fellows and 37 PhD students.
«Cell biology (Growth and Signalling)» Department
Vincent Goffin
Prolactin and Growth Hormone Pathophysiology: Translational Approaches
Franck Oury
Integrative Neurobiology
Mario Pende
Cell growth control by nutrients
Etienne Morel
Autophagy, endomembranes & cellular dynamics in stress response
Marco Pontoglio
Epigenetics and development
Isabelle Sermet Gaudelus
Cystic fibrosis and other epithelial respiratory protein misfolding diseases
Fabiola Terzi
Mecanisms and therapeutic strategies of chronic kidney disease
Guillaume Canaud
Translational and personalized medicine laboratory
Ganna Panasyuk
Mechanisms of Nutrient Sensing
Nicolas Venteclef
Immunity and Metabolism in Diabetes
«Immunology, infectiology and Haematology (I2H)» Department
Laurence Arbibe
Genome plasticity and infections
Elizabeth Macintyre & Vahid Asnafi
Normal and pathological lymphoid differentiation
Lucienne Chatenoud & Maria Leite-De-Moraes
Immunoregulation and Immunopathology
Xavier Nassif & Alain Charbit
Pathogenesis of systemic infections
Peter Van Endert
Innate and adaptive immune pathways in autoimmunity and autoinflammation
Simon Fillatreau
Immunity in health and disease
Pamela Schnupf
Host-Microbiota Interaction
Benedicte Manoury
Immune Response and Danger Signals
Sagi Shapira
Systems Biology Laboratory
Pablo Vargas
Leukomotion Lab
Matthieu Mahevas
Auto-immune and Immune B cells, AI2B
ERC grantees
Current ERC grantees
  • Guillaume CANAUD : ERC Papastudy - Podocyte Adaptation Proliferation and Ageing
  • Simon FILLATREAU : ERC - PREG-LAB - Distinctive characterization of regulatory plasma cells and pro-inflammatory B cells in immunity: their origins, molecular properties, and cellular fates
  • Ganna PANASYUK : ERC MetaboSENS - Metabolic integration by nutrient SENSing
  • Claude-Agnès REYNAUD : ERC B-RESPONSE : Memory and innate-like B-cell subsets: deciphering a multi-layered B-cell response in mice and humans
  • Pamela SCHNUPF : ERC NICHEADAPT - Deciphering the niche adaptations of a gut commensal involved in educating the host immune system
Former ERC grantees
  • Jean-François  BACH : ERC HYGIENE - The hygiene hypothesis: revisiting the concept by integrating epidemiology and mechanistic studies
  • Mario PENDE : ERC RariTOR - mTOR pathophysiology in rare human diseases
  • Jean-Claude WEILL : ERC Advanced - MEMO-B : The B cell memory program: cell fate determinants and functional diversity of B cell subsets
Administration General Services

The administrative platform is led by the General Secretary with the assistance of the financial management. Its mission is the management of human resources, finance and movable heritage. It also coordinates the general kitchen and washroom services, prevention & safety, technology transfer and development, informatics.

Sabine Barbut
General Secretary
Josiane Sage-Preat
Administrative and financial Director

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HRH Princess Caroline of Hanover, who through the Princess Grace Foundation, already supports medical research and anything that helps to relieve the sick children in France and around the world, has agreed to commit to our side so that our Center of Molecular medicine continues to meet the current challenges and fight diseases, and in particular the ones affecting children.

INEM - Organigramme