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Franck OURY
PHD HDR
Integrative Neurobiology - Responsable d'équipe
0664170371
Inserm
Directeur·trice de recherche

Biosketch

Franck Oury earned a degree in neurobiology from Louis Pasteur University-Strasbourg in 2007. During that time, he conducted research in the laboratory of Filippo Rijli at Institut de Génétique et Biologie Moléculaire et Cellulaire (IGBMC), where he revealed the crucial role of homeobox transcription factors in sensory neuronal connectivity.
Following this, Franck Oury advanced his expertise at Columbia University - Medical Center in New York, working under Gerard Karsenty. Here, he explored neuro- and integrative-physiology, discovering novel endocrine functions of the skeleton in regulating gonadal, pancreatic, and brain functions.

In 2014, Franck Oury established his own research group at the Institut Necker Enfants Malades (INEM) in Paris. He secured a permanent INSERM position as CR1 in 2014, later promoted to DR2 in 2019.  His work is supported by multiple grants, including ATIP-Avenir, HFSP, FRM, ANR, INSERM Transfert, Allianz, Emergence de la ville de Paris, European foundation of diabetes, AGEMED, and the FSER program.

Franck Oury’s team takes an interdisciplinary approach, combining neurobiology, cell biology, endocrinology, and integrative physiology to investigate how hormonal factors modulate brain functions. The lab recently made significant contributions to understanding the essential role of systemic factors in maintaining neuronal homeostasis, brain plasticity, and cognitive fitness. Notably, his work identified Osteocalcin (Ocn) as a bone-derived hormone crucial for regulating hippocampal-dependent memory and brain aging. His ongoing research focuses on developing novel therapeutic strategies for age-related cognitive disorders and related conditions.